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CORO2B anticorps

CORO2B Reactivité: Humain, Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7248476
  • Antigène Voir toutes CORO2B Anticorps
    CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
    Reactivité
    • 31
    • 14
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 28
    • 2
    • 1
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CORO2B est non-conjugé
    Application
    • 22
    • 14
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of human CORO2B
    Isotype
    IgG
  • Indications d'application
    WB 1:1000-1:5000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.5 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
    Autre désignation
    CORO2B (CORO2B Produits)
    Synonymes
    anticorps CLIPINC, anticorps E130012P22Rik, anticorps CORO2B, anticorps coro2b, anticorps Coronin-2B, anticorps coronin 2B, anticorps coronin, actin binding protein, 2B, anticorps coronin, actin binding protein, 2Ba, anticorps coronin-2B, anticorps coronin, actin binding protein, 2B L homeolog, anticorps CORO2B, anticorps Coro2b, anticorps coro2b, anticorps coro2ba, anticorps LOC100342263, anticorps coro2b.L
    Sujet
    Coronins are a family of WD repeat-containing, actin-binding proteins that localize to submembraneous areas and regulate cell motility and cytoskeletal rearrangement. Coronin 1A (CORO1A, CLIPINA, CLABP, TACO, p57) can form coiled coil-mediated homotrimeric complexes that influence early phagosome formation. PKC-dependent phosphorylation of Coronin 1B (CORO1B) at Serine 2 regulates leading edge dynamics and cell motility in fibroblasts through interactions with Arp2/3 complex. Coronin 1C (CORO1C, Coronin 3, HCRNN4) is abundant in differentiating Neuro-2a cells, PC-12 cells and primary oligodendrocytes, where it is thought to influence neuron morphogenesis and migration. Coronin 2A (CORO2A, CLIPINB, IR10, WDR2) is a component of the approximately 1.5-2 megadalton N-CoR (nuclear receptor corepressor) complex of 10-12 proteins, which recruits HDACs to generate repressive chromatin. Coronin 7 (CORO7, CRN7) localizes to the Golgi membrane and influences the organization of intracellular membrane compartments and vesicular trafficking. Coronin 2B (CORO2B, CLIPINC) and Coronin 6 (CORO6) are similar to other members of this family, since they possess a conserved basic N-terminal motif and 3-10 WD repeats clustered in one to two core domains.
    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 55 kDa

    UniProt
    Q9UQ03
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