CORO2B anticorps
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- Antigène Voir toutes CORO2B Anticorps
- CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CORO2B est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Synthetic peptide of human CORO2B
- Isotype
- IgG
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- Indications d'application
- WB 1:1000-1:5000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.5 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
- Autre désignation
- CORO2B (CORO2B Produits)
- Synonymes
- anticorps CLIPINC, anticorps E130012P22Rik, anticorps CORO2B, anticorps coro2b, anticorps Coronin-2B, anticorps coronin 2B, anticorps coronin, actin binding protein, 2B, anticorps coronin, actin binding protein, 2Ba, anticorps coronin-2B, anticorps coronin, actin binding protein, 2B L homeolog, anticorps CORO2B, anticorps Coro2b, anticorps coro2b, anticorps coro2ba, anticorps LOC100342263, anticorps coro2b.L
- Sujet
- Coronins are a family of WD repeat-containing, actin-binding proteins that localize to submembraneous areas and regulate cell motility and cytoskeletal rearrangement. Coronin 1A (CORO1A, CLIPINA, CLABP, TACO, p57) can form coiled coil-mediated homotrimeric complexes that influence early phagosome formation. PKC-dependent phosphorylation of Coronin 1B (CORO1B) at Serine 2 regulates leading edge dynamics and cell motility in fibroblasts through interactions with Arp2/3 complex. Coronin 1C (CORO1C, Coronin 3, HCRNN4) is abundant in differentiating Neuro-2a cells, PC-12 cells and primary oligodendrocytes, where it is thought to influence neuron morphogenesis and migration. Coronin 2A (CORO2A, CLIPINB, IR10, WDR2) is a component of the approximately 1.5-2 megadalton N-CoR (nuclear receptor corepressor) complex of 10-12 proteins, which recruits HDACs to generate repressive chromatin. Coronin 7 (CORO7, CRN7) localizes to the Golgi membrane and influences the organization of intracellular membrane compartments and vesicular trafficking. Coronin 2B (CORO2B, CLIPINC) and Coronin 6 (CORO6) are similar to other members of this family, since they possess a conserved basic N-terminal motif and 3-10 WD repeats clustered in one to two core domains.
- Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 55 kDa
- UniProt
- Q9UQ03
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