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ALKBH8 anticorps

ALKBH8 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7249214
  • Antigène Voir toutes ALKBH8 Anticorps
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Reactivité
    • 19
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 34
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALKBH8 est non-conjugé
    Application
    • 13
    • 13
    • 10
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Full length fusion protein
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH8 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    Autre désignation
    ALKBH8 (ALKBH8 Produits)
    Synonymes
    anticorps ABH8, anticorps 4930562C03Rik, anticorps 8030431D03Rik, anticorps 9430088N01Rik, anticorps Abh8, anticorps alkB homolog 8, tRNA methyltransferase, anticorps ALKBH8, anticorps Alkbh8
    Sujet
    ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 75 kDa

    UniProt
    Q96BT7
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