ALKBH8 anticorps

N° du produit ABIN7249214

Détail du produit anti-ALKBH8 anticorps

Antigène: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH8

Antigène: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Autre désignation: ALKBH8 (ALKBH8 Produits)

Synonymes: anticorps ABH8, anticorps 4930562C03Rik, anticorps 8030431D03Rik, anticorps 9430088N01Rik, anticorps Abh8, anticorps alkB homolog 8, tRNA methyltransferase, anticorps ALKBH8, anticorps Alkbh8

Sujet: ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 75 kDa

UniProt: Q96BT7