s100a4 anticorps
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- Antigène Voir toutes s100a4 (S100A4) Anticorps
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp s100a4 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Attributs du produit
- Monoclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse S100A4
- Clone
- 3A6H9
- Isotype
- IgG
- Top Product
- Discover our top product S100A4 Anticorps primaire
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- Indications d'application
- IHC 1:200-1:800
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- Autre désignation
- S100A4 (S100A4 Produits)
- Sujet
- S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
- UniProt
- P26447, P07091, P05942
- Pathways
- S100 Proteins
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