ALPL anticorps

N° du produit ABIN7250008

Détail du produit anti-ALPL anticorps

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse Alkaline Phosphatase

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 200 μg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: ALPL (ALPL Produits)

Synonymes: anticorps ALP, anticorps iap, anticorps alpl, anticorps AP-TNAP, anticorps APTNAP, anticorps HOPS, anticorps TNAP, anticorps TNSALP, anticorps Akp-2, anticorps Akp2, anticorps PHOA, anticorps TNS-AP, anticorps alkaline phosphatase, liver/bone/kidney L homeolog, anticorps alkaline phosphatase, liver/bone/kidney, anticorps alkaline phosphatase, intestinal, gene 2, anticorps alkaline phosphatase, liver/bone/kidney pseudogene, anticorps alpl.L, anticorps ALPL, anticorps alpi.2, anticorps LOC100031702, anticorps Alpl

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

Poids moléculaire:

Observed_MW: 55 kDa

Calculated_MW: 57 kDa

UniProt: P05186, P09242, P08289