KIF7 anticorps

N° du produit ABIN7250092

Détail du produit anti-KIF7 anticorps

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIF7 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Attributs du produit: Monoclonal Antibody

Purification: Protein A purification

Immunogène: Synthetic Peptide

Clone: 3I4

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300, IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIF7

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Autre désignation: KIF7 (KIF7 Produits)

Synonymes: anticorps KIF7, anticorps DDBDRAFT_0204609, anticorps DDBDRAFT_0206583, anticorps DDB_0204609, anticorps DDB_0206583, anticorps ACLS, anticorps HLS2, anticorps JBTS12, anticorps UNQ340, anticorps cos2, anticorps costal2, anticorps kinesin family member 7, anticorps KIF7, anticorps kif7, anticorps Kif7

Sujet: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.

UniProt: Q2M1P5

Pathways: Signalisation Hedgehog