MICU1 anticorps

N° du produit ABIN7250269

Détail du produit anti-MICU1 anticorps

Antigène: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MICU1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Attributs du produit: Monoclonal Antibody

Purification: Protein A purification

Immunogène: Recombinant Protein

Clone: 4E7

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MICU1

Antigène: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Autre désignation: MICU1 (MICU1 Produits)

Synonymes: anticorps CALC, anticorps CBARA1, anticorps EFHA3, anticorps C730016L05Rik, anticorps Calc, anticorps Cbara1, anticorps mitochondrial calcium uptake 1, anticorps MICU1, anticorps Micu1

Sujet: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

Poids moléculaire: 55 kDa

UniProt: Q9BPX6