RORC anticorps

N° du produit ABIN7251244

Détail du produit anti-RORC anticorps

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human RORC

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: RORC (RORC Produits)

Synonymes: anticorps NR1F3, anticorps RORG, anticorps RZR-GAMMA, anticorps RZRG, anticorps TOR, anticorps Nr1f3, anticorps RORgamma, anticorps Thor, anticorps RAR related orphan receptor C, anticorps RAR-related orphan receptor C, anticorps RAR-related orphan receptor gamma, anticorps RORC, anticorps Rorc

Sujet: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.RORC (RAR Related Orphan Receptor C) is a Protein Coding gene. Diseases associated with RORC include Immunodeficiency 42 and Anus Cancer. Among its related pathways are Circadian rythm related genes and Innate Immune System. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and steroid hormone receptor activity. An important paralog of this gene is RORA.

Poids moléculaire:

Observed_MW: 58 kDa

Calculated_MW: 58 kDa

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway