SPI1 anticorps

N° du produit ABIN7251703

Détail du produit anti-SPI1 anticorps

Antigène: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human SPI1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPI1

Antigène: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Autre désignation: SPI1 (SPI1 Produits)

Synonymes: anticorps OF, anticorps PU.1, anticorps SFPI1, anticorps SPI-1, anticorps SPI-A, anticorps Dis-1, anticorps Dis1, anticorps Sfpi-1, anticorps Sfpi1, anticorps Spi-1, anticorps Tcfpu1, anticorps Tfpu.1, anticorps Pu.1, anticorps cb1086, anticorps pu.1, anticorps pu1, anticorps sfpi1, anticorps si:by184l24.2, anticorps spi1, anticorps SPI1/PU.1, anticorps spi1l, anticorps zgc:152991, anticorps Spi-1 proto-oncogene, anticorps spleen focus forming virus (SFFV) proviral integration oncogene, anticorps Spi-1 proto-oncogene b, anticorps Spi-1 proto-oncogene a, anticorps SPI1, anticorps Spi1, anticorps spi1b, anticorps spi1a

Sujet: SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.SPI1 (Spi-1 Proto-Oncogene) is a Protein Coding gene. Diseases associated with SPI1 include Inflammatory Diarrhea and Interdigitating Dendritic Cell Sarcoma. Among its related pathways are Validated targets of C-MYC transcriptional repression and C-MYB transcription factor network. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA binding. An important paralog of this gene is SPIB.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 31 kDa

UniProt: P17947

Pathways: Stem Cell Maintenance