LRRC19 anticorps

N° du produit ABIN7252060

Détail du produit anti-LRRC19 anticorps

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC19 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human LRRC19

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LRRC19

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Autre désignation: LRRC19 (LRRC19 Produits)

Synonymes: anticorps 9130022A01Rik, anticorps AI314124, anticorps AL022954, anticorps AW261791, anticorps leucine rich repeat containing 19, anticorps LRRC19, anticorps Lrrc19

Sujet: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 42 kDa

UniProt: Q9H756