GCLC anticorps

N° du produit ABIN7252117

Détail du produit anti-GCLC anticorps

Antigène: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCLC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human GCLC

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GCLC

Antigène: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Autre désignation: GCLC (GCLC Produits)

Synonymes: anticorps GCLC, anticorps gclc, anticorps MGC146287, anticorps 2259, anticorps CG2259, anticorps DmGCLC, anticorps DmGCS, anticorps DmGCSh, anticorps Dmel\\CG2259, anticorps GCL, anticorps GCLc, anticorps GCSh, anticorps Gcs, anticorps Gcsh, anticorps DDBDRAFT_0186120, anticorps DDBDRAFT_0231403, anticorps DDB_0186120, anticorps DDB_0231403, anticorps GCS, anticorps GLCL, anticorps GLCLC, anticorps D9Wsu168e, anticorps GLCL-H, anticorps Ggcs-hs, anticorps Glclc, anticorps cb1049, anticorps fe36e11, anticorps wu:fe36e11, anticorps glutamate-cysteine ligase catalytic subunit, anticorps glutamate-cysteine ligase, catalytic subunit, anticorps Glutamate-cysteine ligase catalytic subunit, anticorps gamma glutamylcysteine synthetase, anticorps glutamate-cysteine ligase, catalytic subunit L homeolog, anticorps glutamate-cysteine ligase, catalytic subunit S homeolog, anticorps gamma-glutamylcysteine synthetase, anticorps GCLC, anticorps gclc, anticorps Gclc, anticorps LbGCS, anticorps gcsA, anticorps gclc.L, anticorps gclc.S, anticorps GSH1

Sujet: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 73 kDa

UniProt: P48506

Pathways: Cell RedoxHomeostasis