Spartan anticorps

N° du produit ABIN7252330

Détail du produit anti-Spartan anticorps

Antigène: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Spartan est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human SPRTN

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Spartan

Antigène: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Autre désignation: SPRTN (C1orf124 Produits)

Synonymes: anticorps Spartan, anticorps c1orf124, anticorps C1orf124, anticorps DDDL1880, anticorps DVC1, anticorps PRO4323, anticorps dJ876B10.3, anticorps C28H1orf124, anticorps SprT-like N-terminal domain, anticorps sprtn, anticorps SPRTN

Sujet: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

UniProt: Q9H040