SAA1 anticorps

N° du produit ABIN7252717

Détail du produit anti-SAA1 anticorps

Antigène: SAA1 (Serum Amyloid A1 (SAA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAA1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human SAA1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SAA1

Antigène: SAA1 (Serum Amyloid A1 (SAA1))

Autre désignation: SAA1 (SAA1 Produits)

Synonymes: anticorps PIG4, anticorps SAA, anticorps SAA2, anticorps TP53I4, anticorps zgc:103580, anticorps SAA1, anticorps Saa-1, anticorps Saa2, anticorps serum amyloid A1, anticorps serum amyloid A, anticorps amyloid protein A, anticorps serum amyloid A protein, anticorps serum amyloid a protein, anticorps serum amyloid A 1, anticorps serum amyloid protein A, anticorps SAA1, anticorps saa, anticorps LOC694827, anticorps Sden_2438, anticorps Mmc1_0571, anticorps Riean_0971, anticorps Saa1, anticorps LOC100009168, anticorps LOC101120204

Sujet: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. SAA1 (Serum Amyloid A1) is a Protein Coding gene. Diseases associated with SAA1 include Amyloidosis Aa and Splenic Artery Aneurysm. Among its related pathways are Peptide ligand-binding receptors and Activated TLR4 signalling. GO annotations related to this gene include heparin binding and chemoattractant activity. An important paralog of this gene is SAA2.

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades