PRKAG2 anticorps

N° du produit ABIN7253299

Détail du produit anti-PRKAG2 anticorps

Antigène: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAG2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PRKAG2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKAG2

Antigène: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Autre désignation: PRKAG2 (PRKAG2 Produits)

Synonymes: anticorps MGC82938, anticorps PRKAG2, anticorps si:ch211-230l11.1, anticorps si:dkey-217f4.2, anticorps AAKG, anticorps AAKG2, anticorps CMH6, anticorps H91620p, anticorps WPWS, anticorps 2410051C13Rik, anticorps AI854673, anticorps protein kinase AMP-activated non-catalytic subunit gamma 2, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog, anticorps 5'-AMP-activated protein kinase subunit gamma-2, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit b, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit, anticorps Prkag2, anticorps PRKAG2, anticorps prkag2.L, anticorps LOC504219, anticorps prkag2b, anticorps prkag2

Sujet: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. PRKAG2 (Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2) is a Protein Coding gene. Diseases associated with PRKAG2 include Glycogen Storage Disease Of Heart, Lethal Congenital and Wolff-Parkinson-White Syndrome. Among its related pathways are RET signaling and Regulation of TP53 Activity. GO annotations related to this gene include protein kinase binding and protein kinase activator activity. An important paralog of this gene is PRKAG1.

UniProt: Q9UGJ0

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, L'effet Warburg