POLD2 anticorps

N° du produit ABIN7253536

Détail du produit anti-POLD2 anticorps

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human POLD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur POLD2

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Autre désignation: POLD2 (POLD2 Produits)

Synonymes: anticorps 50kDa, anticorps p50, anticorps po1D2, anticorps cdc1, anticorps si:dz150f13.3, anticorps zgc:55633, anticorps zgc:77043, anticorps DNA polymerase delta 2, accessory subunit, anticorps polymerase (DNA directed), delta 2, regulatory subunit, anticorps polymerase (DNA directed), delta 2, accessory subunit L homeolog, anticorps POLD2, anticorps Pold2, anticorps pold2.L, anticorps pold2

Sujet: This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 51 kDa

UniProt: P49005

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA