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CBFA2T2 anticorps
CBFA2T2
Reactivité: Humain, Souris
ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7253602
Détail du produit anti-CBFA2T2 anticorps
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Antigène
Voir toutes CBFA2T2 Anticorps
CBFA2T2
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
Reactivité
Toutes les réactivités sur CBFA2T2 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur CBFA2T2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CBFA2T2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CBFA2T2 Anticorps
Cet anticorp CBFA2T2 est non-conjugé
Application
Tous les applications à travers CBFA2T2 Anticorps.
ELISA, Immunohistochemistry (IHC)
Attributs du produit
Polyclonal Antibody
Purification
Antigen affinity purification
Immunogène
Fusion protein of human CBFA2T2
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
IHC 1:50-1:300, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1.08 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur CBFA2T2
(cache)
Antigène
CBFA2T2
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
Autre désignation
CBFA2T2 (CBFA2T2 Produits )
Synonymes
anticorps MTGR1, anticorps A430091M07, anticorps C330013D05Rik, anticorps Cbfa2t2h, anticorps EHT, anticorps ZMYND3, anticorps p85, anticorps XETOR, anticorps cbfa2t2-a, anticorps CBFA2/RUNX1 translocation partner 2, anticorps core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human), anticorps CBFA2/RUNX1 translocation partner 2 L homeolog, anticorps Cbfa2t2, anticorps CBFA2T2, anticorps cbfa2t2.L
Sujet
In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
UniProt
O43439
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