VGLL1 anticorps

N° du produit ABIN7254214

Détail du produit anti-VGLL1 anticorps

Antigène: VGLL1 (Vestigial Like 1 (VGLL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VGLL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human VGLL1

Isotype: IgG

Information d'application

Indications d'application: WB 1:2000-1:10000 ELISA 1:2000-1:20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur VGLL1

Antigène: VGLL1 (Vestigial Like 1 (VGLL1))

Autre désignation: VGLL1 (VGLL1 Produits)

Synonymes: anticorps TDU, anticorps VGL1, anticorps RGD1564038, anticorps VGLL1, anticorps vgl1, anticorps Tondu, anticorps vestigial like family member 1, anticorps vestigial-like family member 1, anticorps VGLL1, anticorps Vgll1, anticorps vgll1

Sujet: The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 29 kDa

UniProt: Q99990