TCF7 anticorps

N° du produit ABIN7254304

Détail du produit anti-TCF7 anticorps

Antigène: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human TCF7

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TCF7

Antigène: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Autre désignation: TCF7 (TCF7 Produits)

Synonymes: anticorps TCF-1, anticorps AI465550, anticorps Tcf1, anticorps Xtcf-1, anticorps Xtcf1, anticorps tcf-1, anticorps tcf1, anticorps tcf7, anticorps transcription factor 7, anticorps transcription factor 7, T cell specific, anticorps transcription factor 7 S homeolog, anticorps TCF7, anticorps Tcf7, anticorps tcf7, anticorps tcf7.S

Sujet: This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

UniProt: P36402

Pathways: Signalisation WNT