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ATR anticorps

ATR Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7254349
  • Antigène Voir toutes ATR Anticorps
    ATR (ATR serine/threonine kinase (ATR))
    Reactivité
    • 45
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 5
    • 2
    Lapin
    Clonalité
    • 42
    • 4
    Polyclonal
    Conjugué
    • 30
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATR est non-conjugé
    Application
    • 26
    • 22
    • 19
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of human ATR
    Isotype
    IgG
    Top Product
    Discover our top product ATR Anticorps primaire
  • Indications d'application
    IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.1 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ATR (ATR serine/threonine kinase (ATR))
    Autre désignation
    ATR (ATR Produits)
    Synonymes
    anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr
    Sujet
    The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.
    UniProt
    Q13535
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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