ARHGDIB anticorps

N° du produit ABIN7254544

Détail du produit anti-ARHGDIB anticorps

Antigène: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGDIB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human ARHGDIB

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARHGDIB

Antigène: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Autre désignation: ARHGDIB (ARHGDIB Produits)

Synonymes: anticorps ARHGDIB, anticorps zgc:65966, anticorps arhgdib, anticorps MGC69067, anticorps gdia2, anticorps rhodgi-2, anticorps rhodgi2, anticorps D4, anticorps GDIA2, anticorps GDID4, anticorps LYGDI, anticorps Ly-GDI, anticorps RAP1GN1, anticorps RhoGDI2, anticorps Gdid4, anticorps Rho GDP dissociation inhibitor (GDI) gamma, anticorps Rho GDP dissociation inhibitor (GDI) beta S homeolog, anticorps Rho GDP dissociation inhibitor beta, anticorps Rho GDP dissociation inhibitor (GDI) beta, anticorps Rho, GDP dissociation inhibitor (GDI) beta, anticorps arhgdig, anticorps arhgdib.S, anticorps ARHGDIB, anticorps arhgdib, anticorps Arhgdib

Sujet: ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis