Filamin A anticorps

N° du produit ABIN7255039

Détail du produit anti-Filamin A anticorps

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Filamin A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human FLNA (NP_001104026.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: FLNA (FLNA Produits)

Synonymes: anticorps ABP-280, anticorps ABPX, anticorps CSBS, anticorps CVD1, anticorps FLN, anticorps FLN-A, anticorps FLN1, anticorps FMD, anticorps MNS, anticorps NHBP, anticorps OPD, anticorps OPD1, anticorps OPD2, anticorps XLVD, anticorps XMVD, anticorps fb98b06, anticorps wu:fb98b06, anticorps wu:fd09g03, anticorps wu:fd49a06, anticorps Dilp2, anticorps F730004A14Rik, anticorps Fln1, anticorps filamin-1, anticorps RGD1560614, anticorps MGC147094, anticorps CG3937, anticorps Cher, anticorps Dmel\\CG3937, anticorps Fil, anticorps joy, anticorps sko, anticorps filamin A, anticorps filamin A, alpha (actin binding protein 280), anticorps filamin, alpha, anticorps filamin-A, anticorps cheerio, anticorps FLNA, anticorps flna, anticorps Flna, anticorps LOC587317, anticorps cher, anticorps LOC100380643

Sujet: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 315 kDa

Calculated_MW: 280 kDa

ID gène: 2316

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location