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beta Arrestin 1 anticorps

ARRB1 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7255095
  • Antigène Voir toutes beta Arrestin 1 (ARRB1) Anticorps
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    Reactivité
    • 68
    • 39
    • 25
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 72
    • 11
    • 1
    Lapin
    Clonalité
    • 65
    • 19
    Polyclonal
    Conjugué
    • 54
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp beta Arrestin 1 est non-conjugé
    Application
    • 70
    • 35
    • 32
    • 27
    • 18
    • 14
    • 13
    • 13
    • 9
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human ARRB1 (NP_004032.2).
    Isotype
    IgG
    Top Product
    Discover our top product ARRB1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200 IF 1:20-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    Autre désignation
    ARRB1 (ARRB1 Produits)
    Sujet
    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
    ID gène
    408
    UniProt
    P49407
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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