ROCK1 anticorps
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- Antigène Voir toutes ROCK1 Anticorps
- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ROCK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- This antibody ist KO validated.
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant fusion protein of human ROCK1 (NP_005397.1).
- Isotype
- IgG
- Top Product
- Discover our top product ROCK1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
- Autre désignation
- ROCK1 (ROCK1 Produits)
- Synonymes
- anticorps LOC100229794, anticorps CG9774, anticorps DROK, anticorps DRhk, anticorps DRok, anticorps Dmel\\CG9774, anticorps Drok, anticorps ROCK, anticorps ROCK-1, anticorps ROCK1, anticorps ROK, anticorps ROKalpha/beta, anticorps Rhk, anticorps RhoK, anticorps Rock, anticorps Rok, anticorps dROK, anticorps dRok, anticorps drok, anticorps 1110055K06Rik, anticorps Rock-I, anticorps P160Rock, anticorps ROCK-I, anticorps P160ROCK, anticorps p160ROCK, anticorps Rho associated coiled-coil containing protein kinase 1, anticorps Rho kinase, anticorps Rho-associated coiled-coil containing protein kinase 1, anticorps Rho-associated, coiled-coil containing protein kinase 1, anticorps ROCK1, anticorps Rok, anticorps Rock1, anticorps rock1
- Sujet
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
- Poids moléculaire
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Observed_MW: 158 kDa
Calculated_MW: 158 kDa
- ID gène
- 6093
- UniProt
- Q13464
- Pathways
- Dynamique des Microtubules, Signalisation WNT, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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