LOXL1 anticorps

N° du produit ABIN7255189

Détail du produit anti-LOXL1 anticorps

Antigène: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LOXL1 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human LOXL1 (NP_005567.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LOXL1

Antigène: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Autre désignation: LOXL1 (LOXL1 Produits)

Synonymes: anticorps LOL, anticorps LOXL, anticorps Loxl, anticorps si:ch211-238c15.1, anticorps lol, anticorps loxl, anticorps loxl-1, anticorps oxl-1, anticorps lysyl oxidase like 1, anticorps lysyl oxidase-like 1, anticorps lysyl oxidase like 1 L homeolog, anticorps LOXL1, anticorps loxl1, anticorps Loxl1, anticorps loxl1.L

Sujet: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

ID gène: 4016

UniProt: Q08397