FAM3B anticorps

N° du produit ABIN7255421

Détail du produit anti-FAM3B anticorps

Antigène: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM3B est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human FAM3B (NP_478066.3).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200 IF 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FAM3B

Antigène: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Autre désignation: FAM3B (FAM3B Produits)

Synonymes: anticorps 2-21, anticorps C21orf11, anticorps C21orf76, anticorps ORF9, anticorps PANDER, anticorps 9030624C24Rik, anticorps D16Jhu19e, anticorps Pander, anticorps RGD1311662, anticorps family with sequence similarity 3 member B, anticorps family with sequence similarity 3, member B, anticorps FAM3B, anticorps Fam3b

Classe de substances: Viral Protein

Sujet: FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78 % sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5 % of the human genome.

ID gène: 54097

UniProt: P58499

Pathways: Hormone Transport