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MYH11 anticorps

MYH11 Reactivité: Humain, Rat, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7255425
  • Antigène Voir toutes MYH11 Anticorps
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Reactivité
    • 36
    • 19
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    Humain, Rat, Souris
    Hôte
    • 31
    • 8
    Lapin
    Clonalité
    • 20
    • 19
    Polyclonal
    Conjugué
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MYH11 est non-conjugé
    Application
    • 12
    • 12
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human MYH11 (NP_001035203.1).
    Isotype
    IgG
    Top Product
    Discover our top product MYH11 Anticorps primaire
  • Indications d'application
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Autre désignation
    MYH11 (MYH11 Produits)
    Synonymes
    anticorps AV071570, anticorps SM1, anticorps SM2, anticorps smMHC, anticorps AAT4, anticorps FAA4, anticorps SMHC, anticorps SMMHC, anticorps myosin, anticorps myh11, anticorps myosin, heavy polypeptide 11, smooth muscle, anticorps myosin heavy chain 11, anticorps myosin, heavy chain 11, smooth muscle, anticorps myosin, heavy chain 11a, smooth muscle, anticorps Myh11, anticorps MYH11, anticorps myh11a
    Sujet
    The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
    ID gène
    4629
    UniProt
    P35749
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