MYH11 anticorps
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- Antigène Voir toutes MYH11 Anticorps
- MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MYH11 est non-conjugé
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Application
- Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human MYH11 (NP_001035203.1).
- Isotype
- IgG
- Top Product
- Discover our top product MYH11 Anticorps primaire
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- Indications d'application
- IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
- Autre désignation
- MYH11 (MYH11 Produits)
- Synonymes
- anticorps AV071570, anticorps SM1, anticorps SM2, anticorps smMHC, anticorps AAT4, anticorps FAA4, anticorps SMHC, anticorps SMMHC, anticorps myosin, anticorps myh11, anticorps myosin, heavy polypeptide 11, smooth muscle, anticorps myosin heavy chain 11, anticorps myosin, heavy chain 11, smooth muscle, anticorps myosin, heavy chain 11a, smooth muscle, anticorps Myh11, anticorps MYH11, anticorps myh11a
- Sujet
- The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
- ID gène
- 4629
- UniProt
- P35749
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