TCF4 anticorps

N° du produit ABIN7255616

Détail du produit anti-TCF4 anticorps

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TCF4 (NP_001077431.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TCF4

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Autre désignation: TCF4 (TCF4 Produits)

Synonymes: anticorps E2-2, anticorps ITF-2, anticorps ITF2, anticorps PTHS, anticorps SEF-2, anticorps SEF2, anticorps SEF2-1, anticorps SEF2-1A, anticorps SEF2-1B, anticorps TCF-4, anticorps bHLHb19, anticorps 5730422P05Rik, anticorps ASP-I2, anticorps E2.2, anticorps ITF-2b, anticorps ME2, anticorps MITF-2A, anticorps MITF-2B, anticorps TFE, anticorps Tcf-4, anticorps TCF7L2, anticorps XE2, anticorps Xtcf-4, anticorps Xtcf4, anticorps e2-A, anticorps tcf-4, anticorps transcription factor 4, anticorps transcription factor 4 S homeolog, anticorps TCF4, anticorps Tcf4, anticorps tcf4, anticorps tcf4.S

Sujet: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Poids moléculaire:

Observed_MW: 60 kDa

Calculated_MW: 48-71 kDa

ID gène: 6925

UniProt: P15884

Pathways: Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus