anticorps OTB1, anticorps OTU1, anticorps AI850305, anticorps fa19h07, anticorps otub1, anticorps wu:fa19h07, anticorps zgc:92839, anticorps MGC131231, anticorps fb17f04, anticorps otub1l, anticorps wu:fb17f04, anticorps zgc:92685, anticorps OTU deubiquitinase, ubiquitin aldehyde binding 1, anticorps OTU domain, ubiquitin aldehyde binding 1, anticorps OTU deubiquitinase, ubiquitin aldehyde binding 1b, anticorps OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog, anticorps similar to HSPC263, anticorps OTU deubiquitinase, ubiquitin aldehyde binding 1a, anticorps OTUB1, anticorps Otub1, anticorps otub1b, anticorps otub1.L, anticorps otub1, anticorps RGD1565010, anticorps otub1a
Sujet
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.