DDX3Y anticorps

N° du produit ABIN7255736

Détail du produit anti-DDX3Y anticorps

Antigène: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX3Y est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DDX3Y (NP_001116137.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DDX3Y

Antigène: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Autre désignation: DDX3Y (DDX3Y Produits)

Synonymes: anticorps DBY, anticorps DDX3Y, anticorps 8030469F12Rik, anticorps D1Pas1-rs1, anticorps Dby, anticorps DEAD-box helicase 3, Y-linked, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked, anticorps DDX3Y, anticorps Ddx3y

Sujet: The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

ID gène: 8653

UniProt: O15523