TARDBP anticorps

N° du produit ABIN7255800

Détail du produit anti-TARDBP anticorps

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TARDBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human TARDBP (NP_031401.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:20-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TARDBP

Antigène: TARDBP (TAR DNA Binding Protein (TARDBP))

Autre désignation: TARDBP (TARDBP Produits)

Synonymes: anticorps TARDBP, anticorps TDP43, anticorps DKFZp459I2127, anticorps tardbp, anticorps ALS10, anticorps TDP-43, anticorps 1190002A23Rik, anticorps C85084, anticorps Tdp43, anticorps wu:fb77f02, anticorps wu:fc52g10, anticorps TAR DNA binding protein, anticorps Tardbp protein, anticorps TAR DNA binding protein L homeolog, anticorps TAR DNA-binding protein 43-like, anticorps TARDBP, anticorps tardbp, anticorps tardbp.L, anticorps Tardbp, anticorps LOC100621383

Sujet: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Poids moléculaire:

Observed_MW: 42 kDa

Calculated_MW: 31 kDa/44 kDa

ID gène: 23435

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion