COASY anticorps

N° du produit ABIN7255964

Détail du produit anti-COASY anticorps

Antigène: COASY (CoA Synthase (COASY))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COASY est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human COASY (NP_079509.5).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COASY

Antigène: COASY (CoA Synthase (COASY))

Autre désignation: COASY (COASY Produits)

Synonymes: anticorps DPCK, anticorps NBP, anticorps PPAT, anticorps UKR1, anticorps pOV-2, anticorps 1300003G02Rik, anticorps Dpck, anticorps Ppat, anticorps Ukr1, anticorps COASY, anticorps zgc:92337, anticorps PPAT/DPCK, anticorps Coenzyme A synthase, anticorps CoA synthase, anticorps bifunctional coenzyme A synthase, anticorps Bifunctional coenzyme A synthase, anticorps COASY, anticorps Coasy, anticorps CpipJ_CPIJ008826, anticorps pco122135, anticorps coasy

Sujet: Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

Poids moléculaire:

Observed_MW: 62 kDa

Calculated_MW: 62 kDa/65 kDa

ID gène: 80347

UniProt: Q13057

Pathways: Ribonucleoside Biosynthetic Process