SMAD7 anticorps
-
- Antigène Voir toutes SMAD7 Anticorps
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SMAD7 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human SMAD7 (NP_005895.1).
- Isotype
- IgG
- Top Product
- Discover our top product SMAD7 Anticorps primaire
-
-
- Indications d'application
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Autre désignation
- SMAD7 (SMAD7 Produits)
- Synonymes
- anticorps CRCS3, anticorps MADH7, anticorps MADH8, anticorps Smad7a, anticorps Madh7, anticorps Smad10, anticorps madh7, anticorps xsmad7, anticorps wu:fj60c10, anticorps SMAD family member 7, anticorps SMAD family member 7 L homeolog, anticorps SMAD7, anticorps Smad7, anticorps smad7.L, anticorps smad7
- Sujet
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
-
Observed_MW: 46 kDa
Calculated_MW: 23 kDa/46 kDa
- ID gène
- 4092
- UniProt
- O15105
- Pathways
- Interferon-gamma Pathway, Cell-Cell Junction Organization
-