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SPTA1 anticorps

SPTA1 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7256054
  • Antigène Voir toutes SPTA1 Anticorps
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Reactivité
    • 24
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 16
    • 9
    Lapin
    Clonalité
    • 13
    • 12
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPTA1 est non-conjugé
    Application
    • 16
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human SPTA1 (NP_003117.2).
    Isotype
    IgG
    Top Product
    Discover our top product SPTA1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Autre désignation
    SPTA1 (SPTA1 Produits)
    Synonymes
    anticorps Spna1, anticorps AF093576, anticorps AI451697, anticorps Spna-1, anticorps ha, anticorps ihj, anticorps nmf4, anticorps sph, anticorps EL2, anticorps HPP, anticorps HS3, anticorps SPH3, anticorps SPTA, anticorps spectrin, alpha, erythrocytic 1, anticorps spectrin alpha, erythrocytic 1, anticorps Spta1, anticorps SPTA1
    Sujet
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
    ID gène
    6708
    UniProt
    P02549
    Pathways
    Regulation of Actin Filament Polymerization
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