anticorps PDIA2, anticorps DKFZp468D2220, anticorps 1810041F13Rik, anticorps AI661267, anticorps Pdip, anticorps Pdipl, anticorps PDA2, anticorps PDI, anticorps PDIP, anticorps PDIR, anticorps protein disulfide isomerase family A member 2, anticorps protein disulfide isomerase associated 2, anticorps protein disulfide isomerase family A, member 2, anticorps PDIA2, anticorps Pdia2
Sujet
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity.