UNC13D anticorps

N° du produit ABIN7256664

Détail du produit anti-UNC13D anticorps

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13D est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human UNC13D (NP_954712.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UNC13D

Antigène: UNC13D (Unc-13 Homolog D (UNC13D))

Autre désignation: UNC13D (UNC13D Produits)

Synonymes: anticorps FHL3, anticorps HLH3, anticorps HPLH3, anticorps Munc13-4, anticorps UNC13D, anticorps 2610108D09Rik, anticorps Jinx, anticorps mFLJ00067, anticorps Unc13h4, anticorps BIGH3, anticorps CDB1, anticorps CDG2, anticorps CDGG1, anticorps CSD, anticorps CSD1, anticorps CSD2, anticorps CSD3, anticorps EBMD, anticorps LCD1, anticorps unc-13 homolog D, anticorps unc-13 homolog D (C. elegans), anticorps transforming growth factor beta induced, anticorps UNC13D, anticorps Unc13d, anticorps TGFBI, anticorps unc13d, anticorps un13d

Sujet: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Poids moléculaire:

Observed_MW: 123 kDa

Calculated_MW: 41 kDa/123 kDa/128 kDa

ID gène: 201294

UniProt: Q70J99

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process