desert Hedgehog anticorps

N° du produit ABIN7256690

Détail du produit anti-desert Hedgehog anticorps

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp desert Hedgehog est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DHH (NP_066382.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur desert Hedgehog

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Autre désignation: DHH (DHH Produits)

Synonymes: anticorps GDXYM, anticorps HHG-3, anticorps SRXY7, anticorps C78960, anticorps Xchh, anticorps chh, anticorps chh-a, anticorps dhh, anticorps dhh-1, anticorps dhh-A, anticorps hh4, anticorps x-chh, anticorps desert hedgehog, anticorps desert hedgehog L homeolog, anticorps desert hedgehog S homeolog, anticorps DHH, anticorps dhh, anticorps Dhh, anticorps dhh.L, anticorps dhh.S

Classe de substances: Species

Sujet: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Poids moléculaire:

Observed_MW: 44 kDa

Calculated_MW: 43 kDa

ID gène: 50846

UniProt: O43323

Pathways: Signalisation Hedgehog