PIWIL4 anticorps

N° du produit ABIN7256712

Détail du produit anti-PIWIL4 anticorps

Antigène: PIWIL4 (Piwi-Like 4 (PIWIL4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIWIL4 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PIWIL4 (NP_689644.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PIWIL4

Antigène: PIWIL4 (Piwi-Like 4 (PIWIL4))

Autre désignation: PIWIL4 (PIWIL4 Produits)

Synonymes: anticorps HIWI2, anticorps MIWI2, anticorps 9230101H05Rik, anticorps Miwi2, anticorps piwi like RNA-mediated gene silencing 4, anticorps piwi-like RNA-mediated gene silencing 4, anticorps PIWIL4, anticorps Piwil4

Sujet: PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

Poids moléculaire:

Observed_MW: 105 kDa

Calculated_MW: 52 kDa/56 kDa/96 kDa

ID gène: 143689

UniProt: Q7Z3Z4