RELB anticorps (AA 401-500)

N° du produit ABIN700825

Détail du produit anti-RELB anticorps

Antigène: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Épitope: AA 401-500

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RELB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RelB

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-RELB (ABIN700825)

Ta, Schwensen, Liuwantara, Huso, Watnick, Rangan: "Constitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats." dans: World journal of nephrology, Vol. 5, Issue 4, pp. 339-57, (2016) (PubMed).

Détails sur RELB

Antigène: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Autre désignation: RelB (RELB Produits)

Synonymes: anticorps shep, anticorps I-REL, anticorps IREL, anticorps REL-B, anticorps XRelB, anticorps relb-A, anticorps GC-rich, anticorps avian reticuloendotheliosis viral (v-rel) oncogene related B, anticorps RELB proto-oncogene, NF-kB subunit, anticorps v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog, anticorps Relb, anticorps RELB, anticorps relb.S

Sujet:

Synonyms: I REL, IREL, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, RelB, Reticuloendotheliosis viral oncogene homolog B, Transcription factor RelB, v rel avian reticuloendotheliosis viral oncogene homolog, v rel reticuloendotheliosis viral oncogene homolog B, RELB_HUMAN, I-Rel.

Background: The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex. For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.

ID gène: 5971

Pathways: Signalisation NF-kappaB, Signalisation RTK