anticorps PICK, anticorps PRKCABP, anticorps Prkcabp, anticorps prkcabp, anticorps MGC131295, anticorps PICK1, anticorps DKFZp470L2127, anticorps protein interacting with PRKCA 1, anticorps protein interacting with C kinase 1, anticorps protein interacting with PRKCA 1 L homeolog, anticorps PICK1, anticorps Pick1, anticorps pick1, anticorps pick1.L
Sujet
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.