CAMLG anticorps
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- Antigène Voir toutes CAMLG Anticorps
- CAMLG (Calcium Modulating Ligand (CAMLG))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CAMLG est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human CAMLG (NP_001736.1).
- Isotype
- IgG
- Top Product
- Discover our top product CAMLG Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Autre désignation
- CAMLG (CAMLG Produits)
- Synonymes
- anticorps MGC53900, anticorps CAML, anticorps AI385748, anticorps Camlg, anticorps Caml, anticorps calcium modulating ligand L homeolog, anticorps calcium modulating ligand, anticorps camlg.L, anticorps CAMLG, anticorps camlg, anticorps Caml, anticorps Camlg
- Sujet
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
- Poids moléculaire
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Observed_MW: 38 kDa
Calculated_MW: 32 kDa
- ID gène
- 819
- UniProt
- P49069
- Pathways
- EGFR Signaling Pathway
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