IDH3B anticorps

N° du produit ABIN7257349

Détail du produit anti-IDH3B anticorps

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3B est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IDH3B (NP_008830.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IDH3B

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Autre désignation: IDH3B (IDH3B Produits)

Synonymes: anticorps H-IDHB, anticorps RP46, anticorps C78231, anticorps zgc:86647, anticorps MGC79028, anticorps IDH1, anticorps IDH3, anticorps isocitrate dehydrogenase 3 (NAD(+)) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta S homeolog, anticorps IDH3B, anticorps Idh3B, anticorps Idh3b, anticorps idh3b, anticorps idh3b.S

Sujet: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

ID gène: 3420

UniProt: O43837