IFI16 anticorps

N° du produit ABIN7257561

Détail du produit anti-IFI16 anticorps

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFI16 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IFI16 (NP_005522.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFI16

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Autre désignation: IFI16 (IFI16 Produits)

Synonymes: anticorps IFNGIP1, anticorps PYHIN2, anticorps IFI16, anticorps Ifitm3l, anticorps Ifitml, anticorps interferon gamma inducible protein 16, anticorps interferon induced transmembrane protein 2, anticorps myeloid cell nuclear differentiation antigen-like protein, anticorps interferon-activable protein 203, anticorps IFI16, anticorps Ifitm2, anticorps LOC100156073, anticorps LOC488622, anticorps Ifi16

Sujet: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 88 kDa

Calculated_MW: 75 kDa/82 kDa/88 kDa

ID gène: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome