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PNP anticorps

NP Reactivité: Humain, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7257591
  • Antigène Voir toutes PNP (NP) Anticorps
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Reactivité
    • 36
    • 11
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 38
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 41
    • 3
    Polyclonal
    Conjugué
    • 25
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PNP est non-conjugé
    Application
    • 25
    • 17
    • 12
    • 9
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human PNP (NP_000261.2).
    Isotype
    IgG
    Top Product
    Discover our top product NP Anticorps primaire
  • Indications d'application
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Autre désignation
    PNP (NP Produits)
    Synonymes
    anticorps NP, anticorps PRO1837, anticorps PUNP, anticorps Np, anticorps AL024301, anticorps AU015798, anticorps Np-1, anticorps Np-2, anticorps Pnp1, anticorps purine nucleoside phosphorylase, anticorps purine-nucleoside phosphorylase, anticorps PNP, anticorps Pnp
    Classe de substances
    Viral Protein
    Sujet
    This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
    ID gène
    4860
    UniProt
    P00491
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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