P-Cadherin anticorps

N° du produit ABIN7257742

Détail du produit anti-P-Cadherin anticorps

Antigène: P-Cadherin (CDH3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CDH3 (NP_001784.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3 (CDH3 Produits)

Synonymes: anticorps CDH3, anticorps Cadherin-3, anticorps AI385538, anticorps Cadp, anticorps Cdhp, anticorps P-cadherin, anticorps Pcad, anticorps CDHP, anticorps HJMD, anticorps PCAD, anticorps E-Cad, anticorps E-cadherin, anticorps EP-cadherin, anticorps XTCAD-1, anticorps c-cadherin, anticorps cadherin-1, anticorps cdh1, anticorps cdh1-b, anticorps cdh3, anticorps cdhc-A, anticorps cdhp, anticorps hjmd, anticorps l-cam, anticorps lcam, anticorps pcad, anticorps uvo, anticorps uvomorulin, anticorps xb-cad, anticorps xcdh1, anticorps CDH15, anticorps K-CAM, anticorps cadherin 3, anticorps cadherin 3 L homeolog, anticorps Cadherin-3, anticorps CDH3, anticorps Cdh3, anticorps cdh3.L, anticorps cdh-3

Sujet: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).

ID gène: 1001

UniProt: P22223