CISH anticorps

N° du produit ABIN7257930

Détail du produit anti-CISH anticorps

Antigène: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CISH est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CISH (NP_659508.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CISH

Antigène: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Autre désignation: CISH (CISH Produits)

Synonymes: anticorps CISH, anticorps cis, anticorps cish.a, anticorps ptk9l, anticorps twf1l, anticorps wu:fk57g04, anticorps zgc:154062, anticorps zgc:91817, anticorps g18, anticorps socs, anticorps cis-1, anticorps cish, anticorps BACTS2, anticorps CIS, anticorps CIS-1, anticorps G18, anticorps SOCS, anticorps AI385595, anticorps CIS1, anticorps Cis, anticorps F17, anticorps F23, anticorps cytokine inducible SH2 containing protein, anticorps cytokine inducible SH2-containing protein, anticorps CISH, anticorps cish, anticorps Cish

Sujet: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

ID gène: 1154

UniProt: Q9NSE2

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus