GSTM3 anticorps

N° du produit ABIN7258332

Détail du produit anti-GSTM3 anticorps

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM3 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GSTM3 (NP_000840.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTM3

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Autre désignation: GSTM3 (GSTM3 Produits)

Synonymes: anticorps GST5, anticorps GSTB, anticorps GSTM3-3, anticorps GTM3, anticorps Fsc2, anticorps mGSTM5, anticorps glutathione S-transferase mu 3, anticorps glutathione S-transferase Mu 3, anticorps glutathione S-transferase, mu 3, anticorps GSTM3, anticorps Gstm3, anticorps LOC479911

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

ID gène: 2947

UniProt: P21266