ICAM5 anticorps

N° du produit ABIN7258626

Détail du produit anti-ICAM5 anticorps

Antigène: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ICAM5 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of mouse Icam5 (NP_032345.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ICAM5

Antigène: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Autre désignation: Icam5 (ICAM5 Produits)

Synonymes: anticorps TLCN, anticorps TLN, anticorps CD50, anticorps ICAM-3, anticorps Icam3, anticorps Tlcn, anticorps ICAM5, anticorps icam5, anticorps tlcn, anticorps tln, anticorps intercellular adhesion molecule 5, anticorps intercellular adhesion molecule 5, telencephalin, anticorps intercellular adhesion molecule 5 L homeolog, anticorps ICAM5, anticorps Icam5, anticorps LOC100511183, anticorps icam5.L

Sujet: ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.

Poids moléculaire:

Observed_MW: 140 kDa

Calculated_MW: 96 kDa

ID gène: 15898

UniProt: Q60625

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location