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INPP5D anticorps (AA 701-800) (Biotin)

INPP5D Reactivité: Humain, Souris, Singe WB, ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN700917
  • Antigène Voir toutes INPP5D Anticorps
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Épitope
    • 18
    • 18
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-800
    Reactivité
    • 89
    • 65
    • 42
    • 19
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Singe
    Hôte
    • 85
    • 5
    Lapin
    Clonalité
    • 75
    • 15
    Polyclonal
    Conjugué
    • 32
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp INPP5D est conjugé à/à la Biotin
    Application
    • 57
    • 20
    • 18
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain, Singe, Souris
    Homologie
    Rat,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SHIP1
    Isotype
    IgG
    Top Product
    Discover our top product INPP5D Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Autre désignation
    SHIP1 (INPP5D Produits)
    Synonymes
    anticorps INPP5D, anticorps 256.t00004, anticorps 13.t00027, anticorps ship, anticorps ship1, anticorps AI323613, anticorps SHIP, anticorps SHIP-1, anticorps SHIP1, anticorps s-SHIP, anticorps SIP-145, anticorps hp51CN, anticorps inositol polyphosphate-5-phosphatase D, anticorps phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, anticorps inositol polyphosphate 5-phosphatase, anticorps inositol polyphosphate-5-phosphatase D L homeolog, anticorps INPP5D, anticorps LOC100446045, anticorps inpp5d, anticorps EHI_159880, anticorps EHI_153490, anticorps inpp5d.L, anticorps LOC100380693, anticorps Inpp5d
    Sujet

    Synonyms: Inositol polyphosphate 5 phosphatase of 145 kDa, 4, 5-trisphosphate 5-phosphatase 1, hp51CN, hSHIP, Inositol polyphosphate 5 phosphatase 145 kDa, Inositol polyphosphate 5 phosphatase, Inositol polyphosphate 5 phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa, INPP 5D, INPP5D, INPP5D protein, MGC104855, MGC142140, MGC142142, p150 ship, p150Ship, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 1, Phosphatidylinositol-3, SH2 containing inositol 5 phosphatase, SH2 containing inositol phosphatase isoform b, SH2 domain containing inositol 5' phosphatase 1, SH2 domain containing inositol phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol-5''-phosphatase 1, SHIP 1, SHIP-1, SHIP1, SHIP1_HUMAN, Signaling inositol polyphosphate 5 phosphatase SIP 145, Signaling inositol polyphosphate 5 phosphatase SIP145, SIP 145, SIP-145, SIP145.

    Background: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.

    ID gène
    3635
    Pathways
    TCR Signaling, BCR Signaling, L'effet Warburg
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