Crk anticorps

N° du produit ABIN7258862

Détail du produit anti-Crk anticorps

Antigène: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Crk est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CRK (NP_058431.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Crk

Antigène: Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Autre désignation: CRK (CRK Produits)

Synonymes: anticorps CG1587, anticorps CRK, anticorps D-CRK, anticorps D-Crk, anticorps DCrk, anticorps Dcrk, anticorps Dmel\\CG1587, anticorps crk, anticorps dCRK, anticorps dCrk, anticorps fb34h10, anticorps fc05a01, anticorps fi19g05, anticorps wu:fb34h10, anticorps wu:fc05a01, anticorps wu:fc54a04, anticorps wu:fi19g05, anticorps zgc:100936, anticorps CRKII, anticorps p38, anticorps Crko, anticorps crk2, anticorps crkII, anticorps v-crk, anticorps P38C-CRK, anticorps Crk-I, anticorps Crk-II, anticorps Crk-III, anticorps Crk3, anticorps CrkIII, anticorps c-Crk, anticorps Crk oncogene, anticorps v-crk avian sarcoma virus CT10 oncogene homolog, anticorps CRK proto-oncogene, adaptor protein, anticorps v-crk avian sarcoma virus CT10 oncogene homolog L homeolog, anticorps v-crk sarcoma virus CT10 oncogene homolog, anticorps Crk, anticorps crk, anticorps CRK, anticorps crk.L

Sujet: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

ID gène: 1398

UniProt: P46108

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor