CMKLR1 anticorps
-
- Antigène Voir toutes CMKLR1 Anticorps
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
-
Reactivité
- Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CMKLR1 est non-conjugé
-
Application
- Western Blotting (WB)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human CMKLR1 (NP_001135815.1).
- Isotype
- IgG
- Top Product
- Discover our top product CMKLR1 Anticorps primaire
-
-
- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Autre désignation
- CMKLR1 (CMKLR1 Produits)
- Synonymes
- anticorps CHEMERINR, anticorps ChemR23, anticorps DEZ, anticorps RVER1, anticorps Gpcr27, anticorps mcmklr1, anticorps si:ch211-240b21.3, anticorps CMLKR1, anticorps Cmklr-1, anticorps GPCR, anticorps chemerin chemokine-like receptor 1, anticorps chemokine-like receptor 1, anticorps CMKLR1, anticorps Cmklr1, anticorps cmklr1
- Sujet
- Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
- Poids moléculaire
-
Observed_MW: 55 kDa
Calculated_MW: 42 kDa
- ID gène
- 1240
- UniProt
- Q99788
-