IFI35 anticorps

N° du produit ABIN7259096

Détail du produit anti-IFI35 anticorps

Antigène: IFI35 (Interferon-Induced Protein 35 (IFI35))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFI35 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IFI35 (NP_005524.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFI35

Antigène: IFI35 (Interferon-Induced Protein 35 (IFI35))

Autre désignation: IFI35 (IFI35 Produits)

Synonymes: anticorps IFI35, anticorps IFP35, anticorps 2010008K16Rik, anticorps AW986054, anticorps ifi-35, anticorps interferon induced protein 35, anticorps interferon-induced protein 35, anticorps IFI35, anticorps ifi35, anticorps Ifi35

Sujet: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.

Poids moléculaire:

Observed_MW: 35 kDa

Calculated_MW: 31 kDa

ID gène: 3430

UniProt: P80217